Dr. Jaap Jan Boelens is the director of the IDMS lab. Dr. Boelens, who is also the Chief of the Pediatric Transplantation and Cellular Therapy Program, came to Memorial Sloan Kettering from UMC Utrecht and the Princess Maxima Center for Pediatric Oncology, where he worked on developing the largest umbilical cord blood transplant program in Europe. His lab in Utrecht also developed and validated multiple PK and PD models for drugs given in the conditioning regimen and they have related drug exposures to immune reconstitution and clinical outcomes. His mission is by individualizing the conditioning regimens to create to most favorable immune milieu for disease control (efficacy) and infection / GvHD control (safety) after transplantation and cellular therapy. At MSKCC, Dr. Boelens continues to find new ways to advance cord blood and other cellular therapies, as well as to create predictive models for response to treatments.